Parkinson's disease is one of the most dangerous neurodegenerative conditions and the fight against it is still ongoing. New research suggests that a combination of two mushrooms – Lion’s Mane (Hericium erinaceus) and Turkey Tail (Coriolus versicolor) – may help protect the brain from this disease. How does it work? Read on to discover what the latest studies say.
Mushrooms in the fight against Parkinson's disease – hope for a natural therapy
Parkinson's disease is a chronic neurodegenerative condition that leads to the damage of nerve cells in the brain responsible for producing dopamine. The result is a progressive loss of motor skills, hand tremors, muscle rigidity, and mood disorders. While traditional pharmacological therapies help alleviate symptoms, they do not stop the progression of the disease. That’s why scientists are turning to natural substances that may assist in treatment and improve the quality of life for patients.
In this context, two mushrooms – Hericium erinaceus (Lion’s Mane) and Coriolus versicolor (Turkey Tail) – have garnered particular interest. Studies on mice models have shown that these mushrooms have strong protective properties that could support the brain in the fight against Parkinson's disease.
How do Lion’s Mane and Turkey Tail mushrooms work?
Neutralizing free radicals
Research results show that the combination of Turkey Tail and Lion’s Mane acts as a natural protective shield for the brain. These mushrooms help neutralize free radicals – harmful molecules that damage brain cells and accelerate degenerative processes. By activating the cellular defense system based on the Nrf2/HO-1 pathway, the body can better handle oxidative stress, one of the main factors in the development of Parkinson’s disease.
Reducing inflammation
These mushrooms also increase the levels of lipoxin A4 – a substance that naturally reduces inflammation in the body. Reducing brain inflammation is critical for Parkinson’s disease because chronic inflammation can lead to further damage of nerve cells.
Neuroprotection and improvement of motor functions
The combination of both mushrooms not only protects nerve cells but also aids in their regeneration. Studies have shown that Hericium erinaceus and Coriolus versicolor reduce damage to dopaminergic neurons, which are particularly vulnerable in Parkinson’s disease. As a result, after treatment with these mushrooms, the mice retained more healthy nerve cells responsible for dopamine production.
Additionally, these mushrooms help reduce the activity of immune cells in the brain, such as astrocytes and microglia, which, when activated for long periods, can contribute to neurodegeneration. Reducing their activity promotes brain health and improves the overall functionality of neurons.
Improving mood and physical activity
Thanks to their anti-inflammatory and neuroprotective effects, the combination of Lion’s Mane and Turkey Tail also had an impact on the general well-being of the mice. In the experiment, the mice treated with the mushrooms showed less apathy, were more inclined to drink sweetened water, suggesting an improvement in mood and increased physical activity.
These results suggest that these mushrooms may also have antidepressant effects, which is particularly important since people with Parkinson’s disease often struggle with mood disorders, such as depression.
Natural support in the fight against Parkinson’s disease
Studies on Lion’s Mane and Turkey Tail indicate that these mushrooms may hold promising potential as natural support in the treatment and prevention of Parkinson’s disease. Their anti-inflammatory, antioxidant, neuroprotective, and even antidepressant properties make them an interesting alternative that could complement traditional therapies.
Although the studies were conducted on animal models, the results are very promising and show that these natural substances could become a valuable element of the diet in the prevention of neurodegenerative diseases.
How to supplement functional mushrooms?
Supplementing with Hericium erinaceus (Lion’s Mane) and Coriolus versicolor (Turkey Tail) mushrooms can offer many health benefits, especially in terms of brain protection and immune system support. To achieve the best results, it is worth choosing liquid extracts that provide precise dosing and quick absorption of active ingredients by the body.
At Ollywell, we offer liquid extracts of mushrooms that contain concentrated forms of Hericium erinaceus and Coriolus versicolor. Our extracts are made from organic crops and undergo careful extraction processes to retain the full potency of bioactive ingredients. The liquid form allows for quick absorption and precise dose adjustment to individual needs.
By supplementing with Ollywell mushrooms, you can count on support for brain health, concentration, and overall body recovery. Regular use of our extracts will help maintain health and vitality, while their natural anti-inflammatory and antioxidant properties will work in favor of your well-being. Ollywell guarantees the highest quality, natural ingredients that will effectively support your body in the daily fight against neuroinflammation and oxidative stress.
Source: Cordaro et al., 2022, "Natural Compounds Such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice," Biomedicines, 10(10), 2505.